MRT System Magnetom Prisma

University of Salzburg

Salzburg | Website

Large equipment

Short Description

The magnet resonance imaging (MRI) or Nuclear Magnetic Resonance (NMR), is a medical imaging technique, which creates through magnetic fields images of the anatomy and the physiological processes of the body. In the neuroradiology the MRT will be mainly used to gain detailed information about the brain, the cranial bone, the spine including the spinal disc, the spinal cord and the periphery nerves. Soft tissues like the brain and inner organs will be reflected on the MRT picture especially well differentiated and rich in contrast, so that details of even millimeter size are still visible.

The Siemens Magnetom Prisma is currently one of the most modern 3,0 Tesla Magnetresonanztomographen. The device contains a gradient strength of 80mT/m with a minimum rise rate of 200mT/m as well as over 64 high frequency canals and the Tim-Technology. The device offers a wide field of application in the area of functional and structural imaging, but also special methods like the diffuse-weighted tractography, which is used, for example, in the planning of surgical procedures (further application fields, please see methods and expertise in the research infrastructure.
In the field of neuro science, active brain areas (mainly based on the blood oxygenation) are determined with a high spatial resolution and color pictured in a morphological 3-dimensional MRT scan. This is due to changes in the magnetic characteristics of the blood through the consumption of blood oxygen in active nerve cells (BOLD effect). By means of passive stimulation from the outside (visual, acoustic, or sensory) or active stimulation from the inside (conscious performance of movements or brainteasers), the activated brain areas can be determined and displayed in 3-dimensional manner.

Contact Person

Dr. Martin Kronbichler

Research Services

Functional imaging during the performance of various tasks like for example visual word recognition, reading, visual object recognition and theory of mind (thoughts about the mental states of other persons)
Examination of various test persons with specific characteristics such as dyslexia, patients in a persistent vegetative state, consciousness disorders, psychological and neurological disorders (schizophrenia, pathological gambling, anorexia nervosa, etc.), comparison of age groups (acquisition of reading in children, cognitive performance in the advanced age, etc.)
Analyses of advertising-effectiveness with regard to the activation differences in audible / visual advertising

The combination of magnetic resonance tomography with other methods, including electroencephalography, transcranial magnetic stimulation, transcranial DC stimulation, eye movement measurements and hormonal analyze.

Pre-surgical examinations of patients by means of structural and functional imaging.

Methods & Expertise for Research Infrastructure

The Siemens Magnetom Prisma 3 Tesla device is used to perform functional and structural MRI examinations with psychological or neurocognitive aims. This process, for example, examines which parts of the brain are active in certain tasks (e.g., reading, judging image material) to conclude about the underlying cognitive processes.
The magnetic resonance tomograph provides a flexible scanning width, which ranges from small measuring fields (e.g. within the brain) to whole-body images.

A special method in magnetic resonance tomography makes it possible to measure the diffusion movement of water molecules in the body or brain tissue. The so called Diffusion tensor imaging (DTI) is a non-invasive method that allows conclusions on the microstructural characteristics of the brain. DTI can, for example, be used to evaluate changes in the diffusion of water molecules into the white substance of the human brain (e.g. caused through training).

Further fields of application are, for example, arterial spin-labeling and perfusion-MRI, etc.

Allocation to Core Facility

Cognitive Neuroscience

Dr. Martin Kronbichler
Centre for Cognitive Neuroscience
0043 662 8044 5130
martin.kronbichler@sbg.ac.at
http://www.uni-salzburg.at/index.php?id=143&MP=143-44821
Please contact the research service of the University of Salzburg (Technologie@sbg.ac.at) or the responsible contact person for this section mentioned further above in the contact section.
Psychology Department, University of Salzburg
Linguistic Department, University of Salzburg
Christian Doppler Klinik, Salzburg
Siemens Austria
Examining voluntary brain activation and resting state connectivity as diagnostic criterion to distinguish patients with preserved consciousness from vegetative state patients using EEG and functional neuroimaging
2011-2014
Trinka E.
Jubiläumsfonds of the National Bank of Austria

Network analysis of functional connectivity in patients with a disorder of consciousness using functional neuroimaging
2011-2014
Kronbichler M.
Scientific Funds of the Paracelsus Private Medical University

Examining voluntary brain activation in patients with disorders of consciousness
Trinka E.
2010-2014
OeNB Fund

Dyslexia: Longitudinal Study of Brain Dysfunctions
2011-2014
Kronbichler M.
FWF – Austrian Science Fund

Neural correlates of thinking about other minds in schizophrenia: Hypo or hypermentalizing?
2014-2016
Kronbichler M.
Scientific Funds of the Paracelsus Medical University
Many neighbors are not silent.fMRI evidence for global lexical activity in visual word recognition
2015
Braun M., Jacobs A. M., Richlan F., Hawelka S., Hutzler F. & Kronbichler M
Frontiers in human neuroscience, 9.
http://dx.doi.org/10.3389/fnhum.2015.00423

Intrinsic functional connectivity differentiates minimally conscious from unresponsive patients
2015
Demertzi A., Antonopoulos G., Heine L., Voss H. U., Crone J.S., de Los Angeles C. ... & Kronbichler M.
Brain, 138(9), 2619-2631
http://dx.doi.org/10.1093/brain/awv169

Differentiating Self-Projection from Simulation during Mentalizing: Evidence from fMRI
2015
Schurz M., Kogler C., Scherndl T., Kronbichler M. & Kühberger A.
PloS one, 10(3), e0121405.
http://dx.doi.org/10.1371/journal.pone.0121405

Impaired consciousness is linked to changes in effective connectivity of the posterior cingulate cortex within the default mode network
2015
Crone J. S., Schurz M., Höller Y., Bergmann J., Monti M., Schmid E. ... & Kronbichler M.
Neuroimage, 110, 101-109
http://dx.doi.org/10.1016/j.neuroimage.2015.01.037

Differential effects of androgenic and anti-androgenic progestins on fusiform and frontal gray matter volume and face recognition performance
2015
Pletzer B., Kronbichler M. & Kerschbaum H.
Brain research, 1596, 108-115
http://dx.doi.org/10.1016/j.brainres.2014.11.025

Criticism hurts everybody, praise only some: Common and specific neural responses to approving and disapproving social-evaluative videos
2016
Miedl S.F., Blechert J., Klackl J., Wiggert N., Reichenberger J., Derntl B. & Wilhelm F. H.
NeuroImage, 132, 138-147
http://dx.doi.org/10.1016/j.neuroimage.2016.02.027

Resting-state and task-based functional brain connectivity in developmental dyslexia
2014
Schurz M., Wimmer H., Richlan F., Ludersdorfer P., Klackl J. & Kronbichler M.
Cerebral Cortex, bhu184
http://dx.doi.org/10.1093/cercor/bhu184

Fixation-related FMRI analysis in the domain of reading research: using self-paced eye movements as markers for hemodynamic brain responses during visual letter string processing
2014
Richlan F., Gagl B., Hawelka S., Braun M., Schurz M., Kronbichler M. Hutzler F.
Cerebral Cortex, 24(10), 2647-2656
http://dx.doi.org/10.1093/cercor/bht117

Abnormalities of functional brain networks in pathological gambling: a graph-theoretical approach
2013
Tschernegg M., Crone J.S., Eigenberger T., Schwartenbeck P., Fauth-Bühler M., Lemènager T. ... & Kronbichler M.
Front Hum Neurosci, 7, 625
http://dx.doi.org/10.3389/fnhum.2013.00625

Existential neuroscience: self-esteem moderates neuronal responses to mortality-related stimuli.
2013
Klackl J., Eva J. & Kronbichler M.
Social cognitive and affective neuroscience, nst167
http://dx.doi.org/10.1093/scan/nst167

Brain activation disturbance for target detection in patients with mild cognitive impairment: an fMRI study
2012
Staffen W., Ladurner G., Höller Y., Bergmann J., Aichhorn M., Golaszewski S. & Kronbichler M.
Neurobiology of aging, 33(5), 1002-e1.
http://dx.doi.org/10.1016/j.neurobiolaging.2011.09.002

Do visual perspective tasks need theory of mind?
2006
Aichhorn M., Perner J., Kronbichler M., Staffen W. & Ladurner G.
Neuroimage, 30(3), 1059-1068
http://dx.doi.org/10.1016/j.neuroimage.2005.10.026

The visual word form area and the frequency with which words are encountered: evidence from a parametric fMRI study
2004
Kronbichler M., Hutzler F., Wimmer H., Mair A., Staffen W. & Ladurner G.
Neuroimage, 21(3), 946-953
http://dx.doi.org/10.1016/j.neuroimage.2003.10.021

Developmental dyslexia: gray matter abnormalities in the occipitotemporal cortex
2008
Kronbichler M., Wimmer H., Staffen W., Hutzler F., Mair A. & Ladurner G.
Human brain mapping, 29(5)
http://dx.doi.org/10.1093/cercor/bhu184