University of Salzburg

Salzburg | Website

Large equipment

Short Description

Orbitrap mass spectrometer with electrospray ionization and nanoelectrospray ionization, control and evaluation by Xcalibur, computer

Contact Person

Prof. Dr. Christian Huber

Research Services

HPLC-MS Measurements

Methods & Expertise for Research Infrastructure

The device is used for accurate mass measurements of directly infused compounds previously separated by liquid chromatography. This methodology is used in drug and metabolism analysis.

Allocation to Core Facility


Prof. Dr. Christian Huber
Fachbereich Biowissenschaften, Schwerpunkt ACBN
0043 662 8044 5738
Please contact the University of Salzburg ( or the responsible contact person for this section mentioned in the contact field.
Predict-IV – Profiling the toxicity of new drugs; a non animal-based approach integrating toxicodynamics and biokinetics
Wolfgang Dekant, Koordinator
Commission of the European Communities

MARINA: Managing the risks of Nanoparticles
Lang Tran, Koordinator
Commission of the European Communities

Doktoratskolleg Immunity in Cancer and Allery; W 1213
Josef Thalhammer, Koordinator
Fonds zur Förderung der wissenschaftlichen Forschung

Christian Doppler Laboratory for Innovative Tools for the Characterization of Biosimilars
Christian Huber, Laborleiter
Christian Doppler Forschungsgesellschaft
Application of integrated transcriptomic, proteomic and metabolomic profiling for the delineation of mechanisms of drug induced cell stress
Wilmes A., Limonciel A., Aschauer L., Moenks K., Bielow C., Leonard M.O., Hamon J., Carpi D., Ruzek S., Handler A., Schmal O., Herrgen K., Bellwon P., Burek C., Truisi G. L., Hewitt P., Di Consiglio E., Testai E., Blaauboer B.J., Guillou C., Huber C.G., Lukas A., Pfaller W., Mueller S.O., Bois F.Y., Dekant W., Jennings P.
Journal of Proteomics

Quantitative HPLC-MS Analysis of Nucleotide Sugars in Plant Cells following Off-Line SPE Sample Preparation
Behmüller R., Forstenlehner I.C., Tenhaken R., Huber C.G.
Analytical and Bioanalytical Chemistry
DOI: 10.1007/s00216-014-7746-3

Rapid and Comprehensive Impurity Profiling of Synthetic Thyroxine by Ultrahigh-Performance Liquid Chromatography−High-Resolution Mass Spectrometry
Neu V., Bielow C., Gostomski I., Wintringer R., Braun R., Reinert K., Schneider P., Stuppner H., Huber C.G.
Analytical Chemistry

Nephron Toxicity Profiling via Untargeted Metabolome Analysis Employing a High-Performance Liquid Chromatography-Mass Spectrometry-Based Experimental and Computational Pipeline
Ranninger C., Rurik M., Limonciel A., Ruzek S., Reischl R., Wilmes A., Jennings P., Dekant W., Kohlbacher O., Huber C.G.
Journal of Biological Chemistry

Site-Specific Characterization and Absolute Quantification of Pegfilgrastim Oxidation by Top-Down High-Performance Liquid Chromatography-Mass Spectrometry
Forstenlehner I., Holzmann J., Toll H., Huber C.G.
Analytical Chemistry
DOI: 10.1021/acs.analchem.5b02029

Chitosan functionalisation of gold nanoparticles encourages particle uptake and induces cytotoxicity and pro-inflammatory conditions in phagocytic cells, as well as enhancing particle interactions with serum components. Journal of Nanobiotechnology
Boyles M.S.P., Kristl T., Andosch A., Zimmermann M., Tran N., Casals E., Himly M., Puntes V., Huber C.G., Lütz-Meindl U., Duschl A.
Journal of Proteomics
DOI: 10.1186/s12951-015-0146-9