Surface Plamson Resonance Imaging Gerät

University of Applied Sciences Upper Austria

Linz | Website

Large equipment

Short Description

Surface Plasmon Resonance is an established tool in the life-sciences sectors. It offers a new generation of label-free biomolecular analysis, providing information on kinetic processes (association and dissociation), binding affinity, analyte concentration and real-time molecule detection. A large variety of bio-interactions can be monitored, such as antibody/antigen, peptide/antibody, DNA/DNA, antibody/bacteria etc. In combination with a spotter, up to several hundreds of different molecules can be immobilized on the sensorchip to take advantage of the multiplexing capabilities for the rapid screening (>100 sensorgrams in parallel) of molecules.
The reactivity of many different species (ligands) submitted to the same environment can be compared with only one sample injection. Optimization studies for biomolecular interaction analysis (immobilization concentration, pH…) are faster – Saving time and consumables.

Contact Person

Johannes Preiner

Research Services

Label free characterization of molecular interactions in terms of association/dissociation rate constants, binding affinity, analyte concentration and real-time molecule detection. For more details please contact the project leader.

Methods & Expertise for Research Infrastructure

SPRi is used to quantify and characterize (in terms of kinetic rate constants) molecular interactions.

Johannes Preiner
Timed Center
+43 50804 55073
johannes.preiner@fh-linz.at
http://www.fh-ooe.at
For details please contact the project leader.