Bioinformatics

University of Salzburg

Salzburg | Website

Core facility (CF)

Short Description

The server infrastructure includes 15 high-performance computers with multi-core processors (up to 3 GHz)
2 x Sun Fire V40z
7 x HP ProLiant
4 x SUN Fire X 4140
1 x supermicro 4 HE Dual
1 s supermicro 1 HE 2x10-core
2 x HE Intel Dual CPU
1 x LYNX CALLEO

The PC infrastructure includes about 20 desktop computers (Linux, Windows, MacOS X)

Contact Person

Prof. Dr. Manfred Sippl

Research Services

The developed methods (protein structure analysis, protein structure comparison, efficient protein structure search, immunoinformatics, etc.) are made available to the scientific community in the form of software and web services.

Methods & Expertise for Research Infrastructure

Storage of protein structure data
Calculation of protein classifications
Development of energy functions for protein structure analysis
Identification of transcription factor binding sites
Immunoinformatics
Software development
Data analysis

In many cases, the results obtained are also provided as a web service to the scientific community.

Prof. Dr. Manfred Sippl
Fachbereich Biowissenschaften
0043 662 8044 5797
manfred.sippl@sbg.ac.at
https://www.came.sbg.ac.at/
Please contact us via science.plus@sbg.ac.at, or contact the responsible person for this section, mentioned in the contact field
MAESTROweb: a web server for structure based protein stability prediction
2016
Laimer J., Hiebl-Flach J., Lengauer D., Lackner P.
Bioinformatics
http://bioinformatics.oxfordjournals.org/content/early/2016/01/27/bioinformatics.btv769.abstract

Structure-Based Characterization of Multiprotein Complexes
2014
Wiederstein M., Gruber M., Frank K., Melo F., Sippl M.J.
Structure
http://dx.doi.org/10.1016/j.str.2014.05.005

D-Light on promoters: a client-server system for the analysis and visualization of cis-regulatory elements
2013
Laimer J., Zuzan C.J., Ehrenberger T., Freudenberger M., Gschwandtner S., Lebherz C., Lackner P.
BMC Bioinformatics
http://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-14-140

Detection of spatial correlations in protein structures and molecular complexes
2012
Sippl M.J., Wiederstein M.
Structure
http://dx.doi.org/10.1016/j.str.2012.01.024

Real space refinement of crystal structures with canonical distributions of electrons
2011
Ginzinger S., Gruber M., Brandstetter H., Sippl M.J.
Structure
http://dx.doi.org/10.1016/j.str.2011.10.011

High-performance signal peptide prediction based on sequence alignment techniques
2008
Frank K., Sippl M.J.
Bioinformatics
http://dx.doi.org/10.1093/bioinformatics/btn422

ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins
2007
Wiederstein M., Sippl M.J.
Nucleic Acids Research
http://dx.doi.org/10.1093/nar/gkm290

NQ-Flipper: recognition and correction of erroneous asparagine and glutamine side-chain rotamers in protein structures
2007
Weichenberger C.X., Sippl M.J.
Nucleic Acids Research
http://dx.doi.org/10.1093/nar/gkm263