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The Core Facility Bioactive Molecules: Screening and Analysis (BMoSA) provides high throughput microbiology screening resources and high-end mass spectrometry for small molecules as well as for polymers.Covering a broad field of expertise, the CF BMoSA is separated into a screening and chemical analysis part. The latter is further divided into small molecule and polymer analysis.
The CF BMoSA screening facility provides hardware and expertise for cooperation projects and contract work. Our robotic liquid handling equipment is especially adapted to perform high throughput searches for bioactive metabolites and enzymes among microorganisms. We further characterize the chemical and biological properties of the found substances.
The CF BMoSA small molecule analysis part is focusing on the field of metabolomics. With the available equipment and methods primary as well as secondary metabolites can be analyzed and quantified. Besides targeted analytics we have broad expertise in untargeted metabolomics studies using high resolution mass spectrometry. In recent years and projects, we gained a lot of experience in the use of stable isotopes in metabolomics studies and developed various workflows for comprehensive untargeted metabolomics studies.
With a 20+ years of experience in applied polymer biotechnology, the BMoSA Polymer analysis team has a vast experience in the analysis of synthetic polymers. The team is covering the whole “plastic cycle” spectrum, focusing in particular on three pillars:
- polymer synthesis: analysis of synthesized aliphatic and aromatic polyesters;
- surface functionalization: analysis of chemical changes;
- depolymerization for recycling: analysis of the oligomers released by enzymatic treatments.
Methods & Expertise for Research Infrastructure
The Core Facility Bioactive Molecules: Screening and Analysis (BMoSA) provides high throughput microbiology screening resources and high-end mass spectrometry for small molecules as well as for polymers.