CS/3D Chirascan Plus CD Spectrometer

University of Salzburg

Salzburg | Website

Large equipment

Short Description

The equipment consists of: APD Solid state detector; Linear dichroism detector; Single cuvette holder with Peltier temperature control; Accessories for fluorescence polarization and fluorescence measurement; Stop-flow unit; Titration unit; Computer; Control and evaluation software

Contact Person

Prof. Dr. Chiara Cabrele

Research Services

Secondary structure analysis of biomolecules in solution

Methods & Expertise for Research Infrastructure

Determination of secondary structure and stability of peptides and proteins
Protein ligand binding studies (determination of thermodynamic and kinetic parameters)

Allocation to Core Facility

Chemical and Structural Biology

Prof. Dr. Chiara Cabrele
Fachbereich Biowissenschaften, Schwerpunkt ACBN
0043 662 8044 7240
Please contact us via science.plus@sbg.ac.at, or contact the responsible person for this section, mentioned in the contact field
Department of Biosciences, University of Salzburg
Department of Ecology and evolution, University of Salzburg
Emory University, Medical School (USA)
International PhD Program "Immunity in Cancer and Allergy"
Thalhamer Josef (Projektleiter), Aberger Fritz, Brandstetter Johann, Duschl Albert, Ferreira Fatima, Gratz Iris, Greil Richard, Hartmann Tanja, Huber Christian, Risch Angela, Wessler Silja

Kofaktor- und Substratabhängige Aktivierung des Gerinnungsfaktors IXa
Brandstetter Johann
Christian Doppler Laboratory for Innovative Tools for the Characterization of Biosimilars
Huber christian (Sprecher), Brandstetter Johann, Cabrele Chiara, Gadermaier Gabriele, Stutz Hanno
CD Forschungsgesellschaft, Sandoz, Thermo Fisher Scientific, BMWFJ
The Recombinant Inhibitor of DNA Binding Id2 Forms Multimeric Structures via the Helix-Loop-Helix Domain and the Nuclear Export Signal
Roschger C, Schubert M, Regl C, Andosch A, Marquez A, Berger T, Huber CG, Lütz-Meindl U, Cabrele C
Int. J. Mol. Sci. 19(4):E1105
DOI: 10.3390/ijms19041105

Targeting of a Helix-Loop-Helix Transcriptional Regulator by a Short Helical Peptide
Roschger C, Neukirchen S, Elsässer B, Schubert M, Maeding N, Verwanger T, Krammer B, Cabrele C
ChemMedChem 12(18):1497
DOI: 10.1002/cmdc.201700305

Impact of the amino acid sequence on the conformation of side chain lactam-bridged octapeptides
Neukirchen S., Krieger V., Roschger C., Schubert M., Elsässer B., Cabrele C.
J. Pept. Sci. 23(7-8):587-596
DOI: 10.1002/psc.2997

Self-recognition behavior of a helix-loop-helix domain by a fragment scan
Beisswenger M, Cabrele C
Biophys. Biochim. Acta 1844(9):1675-83
DOI: 10.1016/j.bbapap.2014.06.015

Replacement of Thr32 and Gln34 in the C-terminal neuropeptide Y fragment 25-36 by cis-cyclobutane and cis-cyclopentane β-amino acids shifts selectivity toward the Y(4) receptor
Berlicki L, Kaske M, Gutiérrez-Abad R, Bernhardt G, Illa O, Ortuño RM, Cabrele C, Buschauer A, Reiser O.
J. Med. Chem. 56(21):8422
DOI: 10.1021/jm4008505