DynaPro Plate Reader II

Vienna Biocenter Core Facilities GmbH (VBCF)

Wien | Website

Large equipment

Short Description

Dynamic Light Scattering (DLS) measures the fluctuation of light scattered by a sample, which can be used to calculate the diffusion coefficient of the sample. The diffusion coefficient can be used to estimate the particle radius, and to detect different species, such as monomers and aggregates, present in the sample. DLS can be used to detect aggregation and to measure changes in the size or distribution of sizes in the sample under different conditions, for example, protein stability in different buffers or protein unfolding during a thermal melt experiment. The Dynapro Plate Reader II can be used for high-throughput measurement of DLS using 384-well or 1536-well plates.

Contact Person

Peggy Stolt-Bergner

Research Services

We offer the following services on this instrument:

training on the Dynapro Plate Reader II
basic DLS measurements
measurement of viscosity
measurement of sample stability over time
measurement of sample thermal melt
measurement of sample tendency to aggregate

Methods & Expertise for Research Infrastructure

training on the Dynapro Plate Reader II
basic DLS measurements
measurement of viscosity
measurement of sample stability over time
measurement of sample thermal melt
measurement of sample tendency to aggregate

Allocation to Core Facility

Protein Technologies

Peggy Stolt-Bergner
Vienna Biocenter Core Facilities (VBCF)
+43 1 7962324 7070
peggy.stolt@vbcf.ac.at
http://www.vbcf.ac.at/protech
The Vienna Biocenter Core Facilities (VBCF) is a research institute providing access to state of the art infrastructure and advanced research services on a fee-for-service basis. Additionally, VBCF core facilities are open to all forms of scientific cooperation. Information on general conditions of cooperation and usage fees is provided upon request.