Mass Spectrometer/Thermo Fisher Scientific/OrbiTrap Exploris 480 2

Vienna Biocenter Core Facilities GmbH (VBCF)

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Large equipment

Short Description

The Mass Spectrometry Facility operates 4 OrbiTrap Exploris 480 mass spectrometer (ThermoFisher), which are used to analyze the major part of the submitted samples. This mass spectrometer uses a high-capacity transfer tube for maximum ion loading, an electrodynamic ion funnel that accommodates and transmits ions over a broader mass range, and a high-field Orbitrap mass analyzer with a resolution of 480000 (FWHM) at m/z 200. The Advanced Peak Determination (APD) algorithm significantly increases the number of precursors available for data-dependent analysis, which in turn results in more MS/MS spectra, and peptide identifications.
Most importantly, the FAIMS-PRO device adds a new dimension of selectivity. The application of FAIMS leads to a reduction of chemical noise, leading to better signal to noise ratios. The interval of instrument cleaning is so far minimum 6-month period. FAIMS-PRO device will be cleaned in a interval of 3 weeks.

Contact Person

Karl Mechtler

Research Services

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Methods & Expertise for Research Infrastructure

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Allocation to Core Facility

Mass Spectrometry

Karl Mechtler
Vienna Biocenter Core Facilities (VBCF)
+43 1 79730 4280
Vienna BioCenter Core Facilities (VBCF) offer state-of-the-art research infrastructure and scientific services to academic research institutes and companies in the field of Life Sciences at Vienna BioCenter and beyond. Our general cooperation conditions are available at (Downloads – VBCF General Cooperation Conditions). Information on usage fees is provided upon request by the core facilities.