Forschungsinfrastruktur

Vienna Biocenter Core Facilities GmbH (VBCF)

Wien | Website

Short Description

The VBCF Preclinical Phenotyping facilitates several behavioral tests and physiological assays to observe a phenotype of genetically modified or pharmacologically treated mice.

Tests and assays include:

- Metabolic Studies
- Motor coordination and balance
- Anxiety/depression-related behaviour
- Learning and Memory
- Pain studies
- Social interactions
- (Neuro)Physiological Analysis (DSI telemetry system)

Contact Person

Sylvia Badurek

Research Services

The Preclinical Phenotyping Facility provides the following services:

- Characterisation of behavioral and metabolic phenotypes of mouse mutants and pharmacologically treated mice
- Experimental planning and design of behavioral test batteries
- Access to a wide range of state-of-the-art behavioral+metabolic testing equipment and paradigms
- Consultation service including training, instruction and assistance
- Protocol development for mouse behavioral models
- Data analysis, interpretation, and reporting

Methods & Expertise for Research Infrastructure

Phenotyping the mouse (in vivo testing) is becoming increasingly important in the complex analysis of genetically manipulated mice. The Preclinical Phenotyping Facility (pcPHENO) at VBCF, Vienna was established in September, 2012. Its primary objective is to provide centralized support and services to investigators developing and studying genetically modified animal models relevant to human diseases.

Equipment

• Kinematic Analyzer MotoRater M
• Phenotyping home cage system PhenoMaster
• Intellicage System
• Catwalk System