GeoMx DSP Analysis Instrument

University of Salzburg

Salzburg | Website

Open for Collaboration

Short Description

A precise molecular understanding of the heterogeneity of tissues of higher organisms is critical to answering a number of key biomedical questions. The GeoMx Digital Spatial Profiler (DSP) station allows detailed molecular analysis of defined areas within complex, heterogeneous tissue samples at both protein and mRNA level in high-plex formats. The technology provides a spatial-molecular picture of complex biological samples by generating total transcriptomes and profiling data for hundreds of validated protein analytes from so-called "regions of interest" of selected tissue sections.This enables researchers to investigate the multiple cellular and molecular interactions, for example between cancer cells, cells of the microenvironment and therapeutically relevant cells of the immune system, with unprecedented precision. The GeoMX DSP Station thus represents a robust and flexible technology platform that enormously accelerates the path from the discovery of biomedically relevant processes to translational research questions.

Contact Person

Univ.- Prof. Dr. Fritz Aberger

Research Services

spatially highly resolved mRNA and protein profiles from defined regions of complex human and murine tissue sections

Methods & Expertise for Research Infrastructure

The Nanostring GeoMX DSP technology extends the methodology of genomics and proteomics to 3D biology. The GeoMX technology allows the creation of spatial expression profiles within histological section preparations of complex human and murine tissues with unprecedented spatial resolution, precision and depth.

Allocation to research infrastructure

Genomics