Kurzbeschreibung
Microarray Scanner. Anwendungsgebiet: Genexpression, Genomanalyse, Aptamere
Ansprechperson
Mark Manuel Somoza
Research Services
Synthesis of custom high-density DNA, RNA and XNA microarrays (up to ~750000 probes/array) for both genomic and non-genomic applications. Microarray processing (hybridization or incubation), scanning (488 nm/fluorescein, 532 nm/Cy3 and 635nm/Cy5 laser excitation) with resolutions of 2.5 to 100 microns, and data extraction.
Methoden & Expertise zur Forschungsinfrastruktur
Microarray Scanner. Anwendungsgebiet: Genexpression, Genomanalyse, Aptamere
Die Nutzungsbedingungen für das Gerät sind zu vereinbaren.
Next-Generation o-Nitrobenzyl Photolabile Groups for Light-Directed Chemistry and Microarray Synthesis
Nicole Kretschy, Ann-Katrin Holik, Veronika Somoza, Klaus-Peter Stengele, Mark M. Somoza, 2015, Angewandte Chemie International Edition, http://onlinelibrary.wiley.com/doi/10.1002/anie.201502125/abstract
Optimized Light-Directed Synthesis of Aptamer Microarrays
Nicole L. W. Franssen-van Hal, Pepijn van der Putte, Klaus Hellmuth, Stefan Matysiak, Nicole Kretschy, Mark M. Somoza, 2013 Analytical Chemistry, http://pubs.acs.org/doi/abs/10.1021/ac400746j
Simultaneous Light-Directed Synthesis of Mirror-Image Microarrays in a Photochemical Reaction Cell with Flare Suppression
Matej Sack, Nicole Kretschy, Barbara Rohm, Veronika Somoza, and Mark M. Somoza, 2013, Analytical Chemistry, http://pubs.acs.org/doi/abs/10.1021/ac4024318
Base-cleavable microarrays for the characterization of DNA and RNA oligonucleotides synthesized in situ by photolithography
Jory Lietard, Nicole Kretschy, Matej Sack, Alexander S. Wahba, Mark M. Somoza, Masad J. Damha, 2014, Chemical Communications, http://pubs.rsc.org/en/content/articlehtml/2014/cc/c4cc05771f
Nicole Kretschy, Ann-Katrin Holik, Veronika Somoza, Klaus-Peter Stengele, Mark M. Somoza, 2015, Angewandte Chemie International Edition, http://onlinelibrary.wiley.com/doi/10.1002/anie.201502125/abstract
Optimized Light-Directed Synthesis of Aptamer Microarrays
Nicole L. W. Franssen-van Hal, Pepijn van der Putte, Klaus Hellmuth, Stefan Matysiak, Nicole Kretschy, Mark M. Somoza, 2013 Analytical Chemistry, http://pubs.acs.org/doi/abs/10.1021/ac400746j
Simultaneous Light-Directed Synthesis of Mirror-Image Microarrays in a Photochemical Reaction Cell with Flare Suppression
Matej Sack, Nicole Kretschy, Barbara Rohm, Veronika Somoza, and Mark M. Somoza, 2013, Analytical Chemistry, http://pubs.acs.org/doi/abs/10.1021/ac4024318
Base-cleavable microarrays for the characterization of DNA and RNA oligonucleotides synthesized in situ by photolithography
Jory Lietard, Nicole Kretschy, Matej Sack, Alexander S. Wahba, Mark M. Somoza, Masad J. Damha, 2014, Chemical Communications, http://pubs.rsc.org/en/content/articlehtml/2014/cc/c4cc05771f