Isothermal Titration Calorimeter/Malvern Panalytical/MicroCalPEAQ

Vienna Biocenter Core Facilities GmbH (VBCF)

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Large equipment

Short Description

Isothermal Titration Calorimetry (ITC) is a method used to analyze biomolecular interactions by measuring the heat change that occurs when two molecules interact. Heat is liberated or absorbed as a result of the redistribution of non-covalent bonds when the interacting molecules go from the free to the bound state. The resulting isotherm is fitted to a binding model to obtain the affinity (KD), stoichiometry (N) and enthalpy of interaction (ΔH). The MicroCal PEAQ-ITC isothermal titration calorimeter from Malvern Instruments has a 200 μL sample cell and provides direct measurement of the heat absorbed or evolved as a result of mixing precise amounts of reactants in liquid samples.

Contact Person

Devid Drechsel

Research Services

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Methods & Expertise for Research Infrastructure

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Allocation to Core Facility

Protein Technologies

Devid Drechsel
Vienna Biocenter Core Facilities (VBCF)
+43 1 7962324 7070
Vienna BioCenter Core Facilities (VBCF) offer state-of-the-art research infrastructure and scientific services to academic research institutes and companies in the field of Life Sciences at Vienna BioCenter and beyond. Our general cooperation conditions are available at (Downloads – VBCF General Cooperation Conditions). Information on usage fees is provided upon request by the core facilities.