LC-IMS-qTOF

University of Natural Resources and Life Sciences Vienna (BOKU)

Wien

Large equipment

Short Description

Series 6560 LC-IMS-QTOFMS. Agilent Technologies.

This is a new generation ion mobility-mass spectrometry system. In addition to the more conventional TOF and QTOF systems, this instrument introduces an additional analytical dimension, i.e. the drift time or collisional cross-section of a compound, which is highly beneficial for the identification of unknown compounds as well as for addressing challenging separations of isomers.

This system offers a mass accuracy of 1 ppm with a spectral resolution of up to 40 000 and is equipped with a robotic sample preparation device enabling on-line sample preparation steps such as derivatization, clean-up or pre-concentration via solid phase extraction.

Contact Person

Stephan Hann

Research Services

• Highly accurate, targeted quantification of metabolites in biotechnological and biological samples based on stable isotope internal standardization
• Non-targeted (differential) metabolomics workflows
• Determination of isotopologue and tandem mass isotopomer fractions for metabolic flux analysis
• Environmental analysis (e.g. non-target pollutant screening and tracing, exposomics)
• Method development expertise for mass spectrometry-based analysis in metabolomics and environmental analysis
• Scientific support for all stages of analytical study design, method planning and execution

Methods & Expertise for Research Infrastructure

One system. Three dimensions.
This system offers the advantage of three dimensions of separation in a single measurement. It combines the power of high-performance liquid chromatography, new ion mobility technology, and a high-resolution accurate mass system. It is well suited for resolving structural isomers, increasing peak capacity, finding and confirming minor components and preserving protein conformations.

Allocation to Core Facility

Core Facility Cellular Analysis

Stephan Hann
Institut für analytische Chemie
+43 1 47654-77114, 77186, 77197
stephan.hann@boku.ac.at
On demand